Drug optimization has enhanced quality of life for many age groups and disabilities. Pharmaceutical organizations are aiming to increase drug discovery and optimization using organic compounds that are also broadly defined as small organic molecules and biologics. A new addition to drug designing, as some would call it, includes utilizing computer aided drug design.
According to experts in the field, computer aided drug design includes advancements in the field of biochemistry, molecular, and cell biology to increase the rapid design and production of drugs.
The study of drug design includes pharmacology and pharmacogenomics. Pharmacology studies how drugs work in the body and genomics focuses on characteristics based on a person’s complete DNA. Pharmacogenomics analyzes genetic factors that influence how drugs work. These two can determine whether a patient is capable of receiving drug therapy.
Drug therapy does not work on all people because of their genetics. Genes influence responsiveness to certain drug elements, such as nutritional state, concomitant drugs or pharmacogenomics. Genes also determine structure and composition in which a drug is receptive by the biology of a person.
Since evidence-based is such a popular research means for any form of business, it is no surprise drug therapy, drug optimization, drug design, whichever you choose to call it, is using evidence-based approaches to predict drug responsiveness based on genetics.
Pharmaceutical organizations are continuing studies in their own research labs. The leaders are advancing drug discovery by providing in vitro and in vivo contract research services.
Drug development services can include a full range of pharmacokinetic and ADME services for IND/NDA, vivarium with skilled technical staff, FDA guidelines for LC-MS/MS method development and validation.
Biochemistry services could be cell-based assays, protein expression, protein purification, ligand binding assays, enzyme inhibitor characterization and mechanism, or biomarker assays.
Bio-analytical services, however similar in semantics, analyzes rapid screening methods, method development and validation, ocular PK, pro-drug and metabolite PK.
Drug discovery is intended to be for the advantage of patients, whether current of future. It is always evolving, eliminating multiple prescriptions for just one, the better one. It is unfortunate to learn how genetics plays a role, but doesn’t it always. It seems worth discovering if your body influences your prescriptions absorption.
It is a complicated field for those not directly engaged or affected. Maybe it is worth researching further how the field of drug optimization is progressing. The chemistry behind it just confuses mind that are not familiar with the jargon. Look for research articles that have made the studies understandable from a consumer perspective.